R34Q (p.Arg34Gln) variant of BRD2 (Bromodomain-containing protein 2)
R34Q (p.Arg34Gln) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R34Q (p.Arg34Gln) variant details
- p.Arg34Gln
- cosmic curated COSV10821
- TOPMed rs1417603316
- gnomAD rs1417603316
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.26
- CADD 32.00
- PolyPhen-2 0.95
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available