R32G (p.Arg32Gly) variant of BRD2 (Bromodomain-containing protein 2)
R32G (p.Arg32Gly) in BRD2 (Bromodomain-containing protein 2) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
R32G (p.Arg32Gly) variant details
- p.Arg32Gly
- rs1777737452
- gnomAD 6-32969290-TA-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.313
- CADD 12.60
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available