Q3L (p.Gln3Leu) variant of BRD2 (Bromodomain-containing protein 2)
Q3L (p.Gln3Leu) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
Q3L (p.Gln3Leu) variant details
- p.Gln3Leu
- TOPMed rs1778214395
- gnomAD rs1778214395
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.14
- CADD 26.10
- PolyPhen-2 0.07
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available