P36S (p.Pro36Ser) variant of BRD2 (Bromodomain-containing protein 2)
P36S (p.Pro36Ser) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
P36S (p.Pro36Ser) variant details
- p.Pro36Ser
- gnomAD rs1225975115
- Missense
- Variant Prioritization Score for Impact Estimate 0.455
- REVEL 0.22
- CADD 23.50
- PolyPhen-2 0.99
- SIFT 0.10
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available