P36L (p.Pro36Leu) variant of BRD2 (Bromodomain-containing protein 2)
P36L (p.Pro36Leu) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
P36L (p.Pro36Leu) variant details
- p.Pro36Leu
- ExAC rs779883033
- TOPMed rs779883033
- gnomAD rs779883033
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.25
- CADD 22.80
- PolyPhen-2 0.99
- SIFT 1.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available