P36A (p.Pro36Ala) variant of BRD2 (Bromodomain-containing protein 2)
P36A (p.Pro36Ala) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
P36A (p.Pro36Ala) variant details
- p.Pro36Ala
- gnomAD rs1225975115
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.17
- CADD 22.80
- PolyPhen-2 0.99
- SIFT 0.37
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available