P24L (p.Pro24Leu) variant of BRD2 (Bromodomain-containing protein 2)
P24L (p.Pro24Leu) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
P24L (p.Pro24Leu) variant details
- p.Pro24Leu
- ESP rs368437378
- ExAC rs368437378
- TOPMed rs368437378
- gnomAD rs368437378
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.12
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available