L2F (p.Leu2Phe) variant of BRD2 (Bromodomain-containing protein 2)
L2F (p.Leu2Phe) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
L2F (p.Leu2Phe) variant details
- p.Leu2Phe
- rs1353504538
- gnomAD 6-32969255-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- CADD 11.60
- Most common in the African/African-American population (allele frequency 0.00014)
- Structural context available
- Literature evidence available