L11F (p.Leu11Phe) variant of BRD2 (Bromodomain-containing protein 2)
L11F (p.Leu11Phe) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L11F (p.Leu11Phe) variant details
- p.Leu11Phe
- TOPMed rs1222181698
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.06
- CADD 23.70
- PolyPhen-2 0.20
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available