E25K (p.Glu25Lys) variant of BRD2 (Bromodomain-containing protein 2)
E25K (p.Glu25Lys) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
E25K (p.Glu25Lys) variant details
- p.Glu25Lys
- ESP rs371937442
- ExAC rs371937442
- TOPMed rs371937442
- gnomAD rs371937442
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.06
- CADD 23.20
- PolyPhen-2 0.04
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 0.00034)
- Structural context available