A17S (p.Ala17Ser) variant of BRD2 (Bromodomain-containing protein 2)
A17S (p.Ala17Ser) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
A17S (p.Ala17Ser) variant details
- p.Ala17Ser
- ExAC rs766690749
- TOPMed rs766690749
- gnomAD rs766690749
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.07
- CADD 21.70
- PolyPhen-2 0.04
- SIFT 0.76
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available