K21E (p.Lys21Glu) variant of BRCA2 (P51587)
K21E (p.Lys21Glu) in BRCA2 (P51587) is a missense change. The record also includes variant effect predictions, population frequency data, and published literature.
K21E (p.Lys21Glu) variant details
- p.Lys21Glu
- gnomAD 13-32316521-A-G
- Missense
- REVEL 0.04
- CADD 1.57
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Literature evidence available