Q98H (p.Gln98His) variant of BRAF (P15056)
Q98H (p.Gln98His) in BRAF (P15056) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
Q98H (p.Gln98His) variant details
- p.Gln98His
- gnomAD rs906516903
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- MetaLR 0.30
- MetaSVM -0.56
- CADD 19.30
- PolyPhen-2 0.95
- SIFT 0.04
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available