N20S (p.Asn20Ser) variant of BRAF (P15056)
N20S (p.Asn20Ser) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, experimental measurements, and structural context.
N20S (p.Asn20Ser) variant details
- p.Asn20Ser
- 1000Genomes rs781085650
- ExAC rs781085650
- gnomAD rs781085650
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- MetaLR 0.21
- MetaSVM -0.91
- CADD 23.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- BRAF Raf-like Ras-binding domain domainome 1.0: score -0.0152