L92F (p.Leu92Phe) variant of BRAF (P15056)
L92F (p.Leu92Phe) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
L92F (p.Leu92Phe) variant details
- p.Leu92Phe
- Ensembl rs2129062285
- Missense
- Variant Prioritization Score for Impact Estimate 0.663
- MetaLR 0.52
- MetaSVM -0.06
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available