G7C (p.Gly7Cys) variant of BRAF (P15056)
G7C (p.Gly7Cys) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G7C (p.Gly7Cys) variant details
- p.Gly7Cys
- gnomAD rs1818685692
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- MetaLR 0.17
- MetaSVM -0.82
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- BRAF Raf-like Ras-binding domain domainome 1.0: score -0.458