G70E (p.Gly70Glu) variant of BRAF (P15056)
G70E (p.Gly70Glu) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G70E (p.Gly70Glu) variant details
- p.Gly70Glu
- Ensembl rs2129073719
- Missense
- Variant Prioritization Score for Impact Estimate 0.633
- MetaLR 0.31
- MetaSVM -0.36
- CADD 23.60
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available
- BRAF Raf-like Ras-binding domain domainome 1.0: score -0.205