G6D (p.Gly6Asp) variant of BRAF (P15056)
G6D (p.Gly6Asp) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G6D (p.Gly6Asp) variant details
- p.Gly6Asp
- 1000Genomes rs2129153461
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- MetaLR 0.18
- MetaSVM -0.96
- CADD 22.40
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available
- BRAF Raf-like Ras-binding domain domainome 1.0: score -0.156