G460R (p.Gly460Arg) variant of BRAF (P15056)
G460R (p.Gly460Arg) in BRAF (P15056) is a missense change. Clinical records from ClinVar and UniProt describe it as likely pathogenic in the context of Cardiofaciocutaneous syndrome 1. The record also includes structural context.
G460R (p.Gly460Arg) variant details
- p.Gly460Arg
- cosmic curated COSV56166
- Ensembl rs2129023724
- Likely pathogenic
- Cardiofaciocutaneous syndrome 1
- Missense
- ClinVar: Likely pathogenic (Cardiofaciocutaneous syndrome 1)
- UniProt: Likely pathogenic
- Structural context available