G32D (p.Gly32Asp) variant of BRAF (P15056)
G32D (p.Gly32Asp) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G32D (p.Gly32Asp) variant details
- p.Gly32Asp
- Ensembl rs730880417
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- MetaLR 0.16
- MetaSVM -0.99
- CADD 17.10
- PolyPhen-2 0.20
- SIFT 0.36
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available
- BRAF Raf-like Ras-binding domain domainome 1.0: score -0.112