G11S (p.Gly11Ser) variant of BRAF (P15056)
G11S (p.Gly11Ser) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G11S (p.Gly11Ser) variant details
- p.Gly11Ser
- cosmic curated COSV56439
- gnomAD rs1225976306
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- MetaLR 0.14
- MetaSVM -1.00
- CADD 22.00
- PolyPhen-2 0.01
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available
- BRAF Raf-like Ras-binding domain domainome 1.0: score -0.0453