E13V (p.Glu13Val) variant of BRAF (P15056)
E13V (p.Glu13Val) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, experimental measurements, and structural context.
E13V (p.Glu13Val) variant details
- p.Glu13Val
- Ensembl rs2129153403
- Missense
- Variant Prioritization Score for Impact Estimate 0.473
- MetaLR 0.19
- MetaSVM -0.90
- CADD 24.10
- PolyPhen-2 0.14
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available
- BRAF Raf-like Ras-binding domain domainome 1.0: score -0.0899