E13G (p.Glu13Gly) variant of BRAF (P15056)
E13G (p.Glu13Gly) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, experimental measurements, and structural context.
E13G (p.Glu13Gly) variant details
- p.Glu13Gly
- cosmic curated COSV10942
- Ensembl rs2129153403
- Missense
- Variant Prioritization Score for Impact Estimate 0.48
- MetaLR 0.22
- MetaSVM -0.77
- CADD 24.70
- PolyPhen-2 0.14
- SIFT 0.01
- Population evidence available
- Structural context available
- BRAF Raf-like Ras-binding domain domainome 1.0: score -0.0899