A29P (p.Ala29Pro) variant of BRAF (P15056)
A29P (p.Ala29Pro) in BRAF (P15056) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A29P (p.Ala29Pro) variant details
- p.Ala29Pro
- Ensembl rs2129153274
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- MetaLR 0.30
- MetaSVM -0.60
- CADD 23.40
- PolyPhen-2 0.61
- SIFT 0.17
- Population evidence available
- Structural context available
- BRAF Raf-like Ras-binding domain domainome 1.0: score -1.05