T59I (p.Thr59Ile) variant of BIN1 (O00499)
T59I (p.Thr59Ile) in BIN1 (O00499) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
T59I (p.Thr59Ile) variant details
- p.Thr59Ile
- ExAC rs755973108
- TOPMed rs755973108
- gnomAD rs755973108
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.13
- CADD 23.70
- PolyPhen-2 0.27
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available