S159Y (p.Ser159Tyr) variant of BIN1 (O00499)
S159Y (p.Ser159Tyr) in BIN1 (O00499) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
S159Y (p.Ser159Tyr) variant details
- p.Ser159Tyr
- ESP rs371755655
- TOPMed rs371755655
- gnomAD rs371755655
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.23
- CADD 26.60
- PolyPhen-2 0.72
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available