P92L (p.Pro92Leu) variant of BIN1 (O00499)
P92L (p.Pro92Leu) in BIN1 (O00499) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
P92L (p.Pro92Leu) variant details
- p.Pro92Leu
- gnomAD rs1458308545
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.32
- CADD 23.40
- PolyPhen-2 0.22
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available