N106S (p.Asn106Ser) variant of BIN1 (O00499)
N106S (p.Asn106Ser) in BIN1 (O00499) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
N106S (p.Asn106Ser) variant details
- p.Asn106Ser
- gnomAD rs1172180320
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.16
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available