T39I (p.Thr39Ile) variant of BDNF (P23560)
T39I (p.Thr39Ile) in BDNF (P23560) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and published literature.
T39I (p.Thr39Ile) variant details
- p.Thr39Ile
- gnomAD 11-27658449-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.468
- REVEL 0.28
- MetaLR 0.40
- MetaSVM -0.30
- CADD 25.60
- PolyPhen-2 0.76
- SIFT 0.26
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Literature evidence available