S45T (p.Ser45Thr) variant of BDNF (P23560)
S45T (p.Ser45Thr) in BDNF (P23560) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and published literature.
S45T (p.Ser45Thr) variant details
- p.Ser45Thr
- gnomAD 11-27658431-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.19
- MetaLR 0.19
- MetaSVM -0.76
- CADD 21.70
- PolyPhen-2 0.16
- SIFT 0.23
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Literature evidence available