S45R (p.Ser45Arg) variant of BDNF (P23560)
S45R (p.Ser45Arg) in BDNF (P23560) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data.
S45R (p.Ser45Arg) variant details
- p.Ser45Arg
- ExAC rs769259549
- gnomAD rs769259549
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.18
- CADD 24.20
- PolyPhen-2 0.52
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 1.7e-05)