S11P (p.Ser11Pro) variant of BDNF (P23560)
S11P (p.Ser11Pro) in BDNF (P23560) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and published literature.
S11P (p.Ser11Pro) variant details
- p.Ser11Pro
- gnomAD 11-27658534-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.36
- MetaLR 0.22
- MetaSVM -0.72
- CADD 27.30
- PolyPhen-2 0.94
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Literature evidence available