R27K (p.Arg27Lys) variant of BDNF (P23560)
R27K (p.Arg27Lys) in BDNF (P23560) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and published literature.
R27K (p.Arg27Lys) variant details
- p.Arg27Lys
- rs982182462
- gnomAD 11-27658569-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.647
- MetaLR 0.40
- MetaSVM -0.26
- CADD 24.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 6e-05)
- Literature evidence available