L6I (p.Leu6Ile) variant of BDNF (P23560)
L6I (p.Leu6Ile) in BDNF (P23560) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data.
L6I (p.Leu6Ile) variant details
- p.Leu6Ile
- gnomAD rs1184013173
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.24
- CADD 23.50
- PolyPhen-2 0.12
- SIFT 0.10
- Most common in the South Asian population (allele frequency 3.5e-05)