L32W (p.Leu32Trp) variant of BDNF (P23560)
L32W (p.Leu32Trp) in BDNF (P23560) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and published literature.
L32W (p.Leu32Trp) variant details
- p.Leu32Trp
- gnomAD 11-27658470-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.36
- MetaLR 0.43
- MetaSVM -0.71
- CADD 26.20
- PolyPhen-2 0.82
- SIFT 0.06
- Population evidence available
- Literature evidence available