V5E (p.Val5Glu) variant of BCR (P11274)
V5E (p.Val5Glu) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
V5E (p.Val5Glu) variant details
- p.Val5Glu
- cosmic curated COSV10589
- TOPMed rs1408782317
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.19
- CADD 25.80
- PolyPhen-2 0.83
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available