S27P (p.Ser27Pro) variant of BCR (P11274)
S27P (p.Ser27Pro) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
S27P (p.Ser27Pro) variant details
- p.Ser27Pro
- gnomAD 22-23181039-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.26
- CADD 24.10
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available