R22S (p.Arg22Ser) variant of BCR (P11274)
R22S (p.Arg22Ser) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
R22S (p.Arg22Ser) variant details
- p.Arg22Ser
- gnomAD 22-23181024-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.07
- CADD 18.70
- PolyPhen-2 0.05
- SIFT 0.29
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available
- Literature evidence available