R22P (p.Arg22Pro) variant of BCR (P11274)
R22P (p.Arg22Pro) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R22P (p.Arg22Pro) variant details
- p.Arg22Pro
- 1000Genomes rs376532812
- ESP rs376532812
- ExAC rs376532812
- TOPMed rs376532812
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.09
- CADD 21.10
- PolyPhen-2 0.18
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available