R22C (p.Arg22Cys) variant of BCR (P11274)
R22C (p.Arg22Cys) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R22C (p.Arg22Cys) variant details
- p.Arg22Cys
- ExAC rs774090412
- gnomAD rs774090412
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.10
- CADD 23.40
- PolyPhen-2 0.47
- SIFT 0.14
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available