P4S (p.Pro4Ser) variant of BCR (P11274)
P4S (p.Pro4Ser) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
P4S (p.Pro4Ser) variant details
- p.Pro4Ser
- gnomAD 22-23180970-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.10
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available
- Literature evidence available