P4L (p.Pro4Leu) variant of BCR (P11274)
P4L (p.Pro4Leu) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P4L (p.Pro4Leu) variant details
- p.Pro4Leu
- TOPMed rs2072241399
- gnomAD rs2072241399
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.13
- CADD 23.50
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available