P21S (p.Pro21Ser) variant of BCR (P11274)
P21S (p.Pro21Ser) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
P21S (p.Pro21Ser) variant details
- p.Pro21Ser
- gnomAD 22-23181021-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.564
- REVEL 0.46
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available