P21L (p.Pro21Leu) variant of BCR (P11274)
P21L (p.Pro21Leu) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
P21L (p.Pro21Leu) variant details
- p.Pro21Leu
- gnomAD 22-23181022-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- REVEL 0.50
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available