P20L (p.Pro20Leu) variant of BCR (P11274)
P20L (p.Pro20Leu) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
P20L (p.Pro20Leu) variant details
- p.Pro20Leu
- gnomAD rs1216823607
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.34
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available