M23R (p.Met23Arg) variant of BCR (P11274)
M23R (p.Met23Arg) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
M23R (p.Met23Arg) variant details
- p.Met23Arg
- gnomAD 22-23181028-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.372
- REVEL 0.28
- CADD 25.10
- PolyPhen-2 0.97
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available