L25Q (p.Leu25Gln) variant of BCR (P11274)
L25Q (p.Leu25Gln) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
L25Q (p.Leu25Gln) variant details
- p.Leu25Gln
- gnomAD rs1418636261
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.43
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available