L25P (p.Leu25Pro) variant of BCR (P11274)
L25P (p.Leu25Pro) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
L25P (p.Leu25Pro) variant details
- p.Leu25Pro
- gnomAD 22-23181034-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.44
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available