K12* (p.Lys12Ter) variant of BCR (P11274)
K12* (p.Lys12Ter) in BCR (P11274) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
K12* (p.Lys12Ter) variant details
- p.Lys12Ter
- gnomAD 22-23180994-A-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.722
- CADD 37.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available