I31S (p.Ile31Ser) variant of BCR (P11274)
I31S (p.Ile31Ser) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
I31S (p.Ile31Ser) variant details
- p.Ile31Ser
- 1000Genomes rs2072244644
- gnomAD rs2072244644
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.30
- CADD 26.80
- PolyPhen-2 0.69
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available